Triethylamine → HCID 9860014, compound

HRID 1376174Notes

Reaction equation

HRID 1376174 reaction equation
Cl[C:2]1[S:3][C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=1.[N:11]1([CH2:17][CH2:18][NH2:19])[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]1.C(N(CC)CC)C>C(O)C>[N:11]1([CH2:17][CH2:18][NH:19][C:2]2[S:3][C:4]3[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=3[N:6]=2)[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]1

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 119872-ChlorobenzothiazoleHCID 33944N-(2-Aminoethyl)piperidine

Product 1

HCID 9860014HCID 9860014, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2-Chlorobenzothiazole (10 mmol), 10 mmol of 2-piperidinoethanamine, and 30 mmol of triethylamine in 50 ml of dry ethanol were refluxed for 6 hours. The product was crystallized with hydrochloric acid in 2-propanol and recrystallized in methanol.

Workup

  1. customThe product was crystallized with hydrochloric acid in 2-propanol
  2. customrecrystallized in methanol

Sources & evidence

ORD record
ord-304cfb96d86843a8a1bf53d1f13d3401
Source dataset
uspto-grants-2007_01
Patent number
US07169928B2

Reaction notes

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