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HRID1377682

反应详情

EQUATION

反应方程式

HRID 1377682 的结构方程式

REACTANTS

反应物

2
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：CC(C)(C)OC(=O)N1CCC(N2C(=O)COc3ccccc32)CC1
HCID22380676

1,1-Dimethylethyl 4-(2,3-dihydro-3-oxo-4H-1,4-benzoxazin-4-yl)-1-piperidinecarboxylate

C18H24N2O4

PRODUCTS

生成物

1
结构：O=C1COc2ccccc2N1C1CCNCC1
HCID22293810

4-(Piperidin-4-yl)-2H-1,4-benzoxazin-3(4H)-one

C13H16N2O2

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCOC(C)=O
溶剂HCID8857

Ethyl acetate

C4H8O2

PROCEDURE

实验过程

4-(1-tert-butyloxycarbonyl-4-piperidinyl)-(2H)-1,4-benzoxazin-3(4H)-one from Step 4 was N-deprotedcted with HCl in EtOAc using the procedure given in Step 4 of Example 1. The hydrochloride salt of 4-(4-piperidinyl)-(2H)-1,4-benzoxazin-3(4H)-one was obtained as a solid (95% yield).