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HRID1377684

反应详情

EQUATION

反应方程式

HRID 1377684 的结构方程式

REACTANTS

反应物

2
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：CC(C)(C)OC(=O)N1CCC(n2c(=O)oc3ccccc32)CC1
HCID22644594

tert-Butyl 4-(2-oxo-1,3-benzoxazol-3(2H)-yl)piperidine-1-carboxylate

C17H22N2O4

PRODUCTS

生成物

1
结构：O=c1oc2ccccc2n1C1CCNCC1
HCID11321928

3-(4-Piperidinyl)-1,3-benzoxazol-2(3H)-one

C12H14N2O2

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCOC(C)=O
溶剂HCID8857

Ethyl acetate

C4H8O2

PROCEDURE

实验过程

3-(1-t-Butyloxycarbonyl-4-piperidinyl)benzoxazolidin-2-one from Step 1 was N-deprotected with HCl in EtOAc using the procedure given in Step 4 of Example 1. The hydrochloride salt of 3-(4-piperidinyl)benzoxazolidin-2-one was obtained as a solid (96% yield).