Potassium Carbonate → 28645-51-4

HRID 1383285Notes

Reaction equation

HRID 1383285 reaction equation
C(=O)([O-])[O-].[K+].[K+].Br[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13]/[CH:14]=[CH:15]\[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][C:23]([OH:25])=[O:24]>CN1CCCC1=O>[O:24]1[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH:14]=[CH:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][C:23]1=[O:25]

Participants

4

Reactant 2

HCID 11430Potassium CarbonateHCID 88227242HCID 88227242, compound

Product 1

HCID 535529328645-51-4Yield 51.2%

Reagents, catalysts & solvents 1

HCID 13387N-methyl-2-pyrrolidoneSolvent2×

Procedure

40 g (0.29 mol) of potassium carbonate were suspended in finely pulverized form in 600 mg of N-methylpyrrolidone. 49 g (0.147 mol) of Z-16-bromohexadec-9-enoic acid in 300 ml of N-methylpyrrolidone were added dropwise within 6 hours. A standard work up was effected; bulb-tube distillation and recrystallization gave 19 g (51%) of 10Z-oxacydoheptadec-10-en-2-one were obtained having the following characteristics: Z/E=98/2;

Workup

  1. distillationbulb-tube distillation and recrystallization

Sources & evidence

ORD record
ord-374752f033fd42c985bb01a3fc648ea9
Source dataset
uspto-grants-2001_07
Patent number
US06255276B1

Reaction notes

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