Methane → HCID 70507384, compound

HRID 1388857Notes

Reaction equation

HRID 1388857 reaction equation
[C:1]([N:4]1[CH2:9][CH2:8][CH:7]([CH2:10][C:11]([OH:13])=[O:12])[CH2:6][CH2:5]1)(=[NH:3])[NH2:2].C.[ClH:15]>>[ClH:15].[C:1]([N:4]1[CH2:9][CH2:8][CH:7]([CH2:10][C:11]([OH:13])=[O:12])[CH2:6][CH2:5]1)(=[NH:2])[NH2:3]

Participants

4

Reactant 3

HCID 297MethaneHCID 313Hydrochloric AcidHCID 15583504HCID 15583504, compound

Product 1

HCID 70507384HCID 70507384, compoundYield 92%

Procedure

11.5 g of 1-amidino-4-piperidineacetic acid prepared in Example 54 was dissolved in 100 ml of a 1 N hydrochloric acid solution, and the solution was treated with activated charcoal and concentrated. Acetone was added to the residue to obtain 12.7 g (yield: 92%) of 1-amidino-4-piperidineacetic acid hydrochloride as colorless prisms having a melting point of 213° to 215.5° C.

Workup

  1. concentrationconcentrated
  2. additionAcetone was added to the residue

Sources & evidence

ORD record
ord-c8e669ab704740b087b53ced628a2ab7
Source dataset
uspto-grants-1984_02
Patent number
US04433152

Reaction notes

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