L-(-)-Sorbose → L-Ascorbic Acid

HRID 1392002Notes

Reaction equation

HRID 1392002 reaction equation
[OH:1][CH2:2][C:3]([C@H:5]([C@@H:7]([C@H:9]([CH2:11][OH:12])[OH:10])[OH:8])[OH:6])=[O:4].C([O-])([O-])=O.[Ca+2]>OCC(CO)O>[OH:6][C:5]1[C@@H:7]([C@@H:9]([OH:10])[CH2:11][OH:12])[O:8][C:2](=[O:1])[C:3]=1[OH:4]

Participants

4

Reactant 2

HCID 6904L-(-)-SorboseHCID 10112Calcium Carbonate

Product 1

HCID 54670067L-Ascorbic Acid

Reagents, catalysts & solvents 1

HCID 753GlycerolSolvent

Procedure

3 ml of the seed culture were transferred into 500 ml Erlenmeyer flasks containing 50 ml of the production medium containing 8.0% L-sorbose, 5.0% baker's yeast, 0.05% glycerol, 0.25% MgSO4.7H2O, 3.0% corn steep liquor, 1.5% CaCO3 and 0.15% antifoam. The cultivation was carried out at 30° C. with 180 rpm for 20 h on a rotary shaker. As a result, 407.1 mg/L of vitamin C was produced.

Workup

  1. additioncontaining 50 ml of the production medium

Sources & evidence

ORD record
ord-4f97fbf496194a6da9ff9801c5071299
Source dataset
uspto-grants-2008_03
Patent number
US07341854B2

Reaction notes

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