Dimethylformamide → 1,1-Dimethylethyl 4-[(1,2,3,4,7,8,9,10-octahydro-2,3-dioxopyrido[3,4-f]quinoxaline-9-yl)carbonyl]-1-piperidine carboxylate

HRID 139301Notes

Reaction equation

HRID 139301 reaction equation
[C:17]([c:18]1[nH:19][cH:20][cH:21][n:22]1)([c:23]1[nH:24][cH:25][cH:26][n:27]1)=[O:28].[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH2:10][CH:11]([C:14](=[O:15])[OH:16])[CH2:12][CH2:13]1.[CH3:45][CH2:46][N:47]([CH2:48][CH3:49])[CH2:50][CH3:51].[CH3:57][N:58]([CH3:59])[CH:60]=[O:61].[O:52]1[CH2:53][CH2:54][CH2:55][CH2:56]1.[nH:29]1[c:30](=[O:44])[c:31](=[O:43])[nH:32][c:33]2[cH:34][cH:35][c:36]3[c:37]([c:38]12)[CH2:39][NH:40][CH2:41][CH2:42]3>>[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH2:10][CH:11]([C:14](=[O:16])[N:40]2[CH2:39][c:37]3[c:36]([cH:35][cH:34][c:33]4[nH:32][c:31](=[O:43])[c:30](=[O:44])[nH:29][c:38]43)[CH2:42][CH2:41]2)[CH2:12][CH2:13]1

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 3928711-(tert-Butoxycarbonyl)-4-piperidinecarboxylic acidHCID 5250894Bis-(1H-imidazol-2-YL)-methanoneHCID 212530731,4,7,8,9,10-Hexahydropyrido[3,4-f]quinoxaline-2,3-dione

Product 1

HCID 212530551,1-Dimethylethyl 4-[(1,2,3,4,7,8,9,10-octahydro-2,3-dioxopyrido[3,4-f]quinoxaline-9-yl)carbonyl]-1-piperidine carboxylate

Sources & evidence

ORD record
ord-fab593d8201d4f6ea82071c50276fe31
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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