Hydrochloric Acid → HCID 69197694, compound

HRID 1393613Notes

Reaction equation

HRID 1393613 reaction equation
[CH2:1](OC1C=CC=CC=1Br)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[Mg].[C:28]([C:36]1[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=1)(=[O:35])[C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1.Cl>C1COCC1>[CH2:1]([O:35][C:28]([C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1)([C:36]1[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=1)[C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 3102BenzophenoneHCID 5462224MagnesiumHCID 69196506HCID 69196506, compound

Product 1

HCID 69197694HCID 69197694, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Octadecyloxytriphenylmethane (C18 Tr-OH) was prepared in a Grignard procedure starting from octadecyloxyphenyl bromide and magnesium in dry THF. Benzophenone was added to the metalorganic compound and the product was hydrolyzed with 2 M HCl. The worked-up reaction mixture was dried, evaporated, and the pure product crystallized from toluene. The trityl alcohol was converted to the trityl chloride by treatment with an excess of acetylchloride.

Workup

  1. customThe worked-up reaction mixture
  2. customwas dried
  3. customevaporated
  4. customthe pure product crystallized from toluene

Sources & evidence

ORD record
ord-44155ee745704771bdca5782cccca451
Source dataset
uspto-grants-2008_03
Patent number
US07345163B2

Reaction notes

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