Methane → HCID 20340333, compound

HRID 1395137Notes

Reaction equation

HRID 1395137 reaction equation
[C:1]([C:3](=[C:10]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[C:4]([O:6][CH2:7][CH2:8][OH:9])=[O:5])#[N:2].[CH2:23]([O:27][CH2:28][CH:29]=[CH2:30])[CH:24]1[O:26][CH2:25]1.C>[Cl-].C[N+](C)(C)C.C(Cl)Cl>[CH2:28]([O:27][CH2:23][CH:24]([OH:26])[CH2:25][O:9][CH2:8][CH2:7][O:6][C:4](=[O:5])[C:3]([C:1]#[N:2])=[C:10]([C:17]1[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=1)[C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=1)[CH:29]=[CH2:30]

Participants

6

Reactant 3

HCID 297MethaneHCID 7838Allyl glycidyl etherHCID 19020936HCID 19020936, compound

Product 1

HCID 20340333HCID 20340333, compound

Reagents, catalysts & solvents 2

HCID 6379Tetramethylammonium chlorideCatalystHCID 6344DichloromethaneSolvent

Conditions

Temperature
50 °C

Procedure

Into a round bottom flask was charged 29 g. (0.1 moles) of 2-hydroxyethyl 2-cyano-3,3-diphenylacrylate, 12.4 g. (0.11 moles) of allyl glycidyl ether and 250 mg. of tetramethylammonium chloride. The flask was stoppered and the mixture was heated at 50° C. for 16 hours. Then cooled mixture was diluted with 50 ml. methylene dichloride, treated with decolonizing charcoal and filtered. The filtrate was evaporated, leaving a pale yellow oil characterized as the product.

Workup

  1. additionInto a round bottom flask was charged 29 g
  2. temperatureThen cooled mixture
  3. additionwas diluted with 50 ml
  4. filtrationfiltered
  5. customThe filtrate was evaporated
  6. customleaving a pale yellow oil

Sources & evidence

ORD record
ord-ff1372e138e041d8a8cbd4a6dadb0c43
Source dataset
uspto-grants-1980_05
Patent number
US04202834

Reaction notes

Loading…