Ethanol → Methyl Acetate

HRID 1395790Notes

Reaction equation

HRID 1395790 reaction equation
CO.[CH2:3]([OH:5])[CH3:4].[C:6]([O:9][CH2:10]C)(=[O:8])[CH3:7].[CH2:12]([OH:15])[CH2:13][CH3:14]>[CH-]=O.[CH-]=O.[C-]#[O+].[C-]#[O+].[C-]#[O+].[C-]#[O+].[C-]#[O+].[C-]#[O+].[Co].[Co+2].C(O)CCC>[CH:6]([O:9][CH3:10])=[O:8].[C:6]([O:9][CH3:10])(=[O:8])[CH3:7].[CH4:3].[C:3]([O:15][CH2:12][CH2:13][CH3:14])(=[O:5])[CH3:4]

Participants

10

Reactant 4

HCID 702EthanolHCID 887MethanolHCID 10311-PropanolHCID 8857Ethyl Acetate

Product 4

HCID 297MethaneYield 8.5%HCID 6584Methyl AcetateYield 9%HCID 7865Methyl formateYield 2%HCID 7997Propyl AcetateYield 0.1%

Reagents, catalysts & solvents 2

HCID 25049Dicobalt Octacarbonyl (stabilized with 1-5% Hexane)CatalystHCID 2631-ButanolSolvent

Procedure

Thus in a paper published in Science 113, 206 (1951) Wender, Friedel and Orchin reported that methanol was reacted with synthesis gas (1H2 :1CO) in the presence of dicobalt octacarbonyl as catalyst to produce methyl formate (2%), methyl acetate (9.0%), ethyl alcohol (38.3%), ethyl acetate (6.3%), propyl alcohol (4.7%), butyl alcohol (0.09%), methane (8.5%), propyl acetate (0.1%) and a small amount of unidentified product, the total conversion of methanol being 76.4% over a reaction period of eight hours.

Sources & evidence

ORD record
ord-038033fdf48d4efe9d5301a64012f28f
Source dataset
uspto-grants-1980_05
Patent number
US04205190

Reaction notes

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