Tetrahydrofuran → Ethyl 4-[[1-[3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperidin-4-yl]oxy]benzoate
Reaction equation
[CH2:66]1[O:67][CH2:68][CH2:69][CH2:70]1.[F:15][C:16]([c:17]1[n:18][n:19][c:20]2[n:21]1[n:22][c:23]([N:26]1[CH2:27][CH2:28][CH:29]([OH:32])[CH2:30][CH2:31]1)[cH:24][cH:25]2)([F:33])[F:34].[O:1]=[C:2]([O:3][CH:4]([CH3:5])[CH3:6])[N:7]=[N:8][C:9]([O:10][CH:11]([CH3:12])[CH3:13])=[O:14].[OH:35][c:36]1[cH:37][cH:38][c:39]([C:40](=[O:41])[O:42][CH2:43][CH3:44])[cH:45][cH:46]1.[c:47]1([P:48]([c:49]2[cH:50][cH:51][cH:52][cH:53][cH:54]2)[c:55]2[cH:56][cH:57][cH:58][cH:59][cH:60]2)[cH:61][cH:62][cH:63][cH:64][cH:65]1>>[F:15][C:16]([c:17]1[n:18][n:19][c:20]2[n:21]1[n:22][c:23]([N:26]1[CH2:27][CH2:28][CH:29]([O:32][c:36]3[cH:37][cH:38][c:39]([C:40](=[O:41])[O:42][CH2:43][CH3:44])[cH:45][cH:46]3)[CH2:30][CH2:31]1)[cH:24][cH:25]2)([F:33])[F:34]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-403aa6862bfe4660a53861a536962881
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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