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HRID1403795

反应详情

EQUATION

反应方程式

HRID 1403795 的结构方程式

REACTANTS

反应物

4
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：O=C(Cl)c1ccc(Cl)cc1
HCID8501

4-Chlorobenzoyl chloride

C7H4Cl2O

结构：CC(C)(C)[Si](C)(C)C(OC(c1cc(Cl)cc(Cl)c1)[Si](C)(C)C(C)(C)C)c1cc(Cl)cc(Cl)c1
HCID67042253

未命名化合物

结构：[Li]CCCC
HCID178418339

Butyllithium

C4H9Li

PRODUCTS

生成物

1
结构：O=C(c1ccc(Cl)cc1)c1c(Cl)cc(CO)cc1Cl
HCID2817766

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：C1CCOC1
溶剂HCID8028

Tetrahydrofuran

C4H8O

结构：CCCCCC
溶剂HCID8058

n-Hexane

C6H14

PROCEDURE

实验过程

React t-Butyldimethylsilyl-3,5-dichlorobenzyl ether (858.A1) (1 mole) with n-Butyllithium 1.6M solution in hexane followed by 4-Chlorobenzoyl chloride, (1.01 mole), in Tetrahydrofuran, while cold and treat the intermediate with aqueous Hydrochloric acid to give 3,5-dichloro-4-(4-chlorobenzoyl)benzyl alcohol (858.B).