Hydroxylamine → 4-(4-Bromo-2-chloro-phenoxy)-benzaldehyde-oxime

HRID 1406359Notes

Reaction equation

HRID 1406359 reaction equation
[Br:1][C:2]1[CH:16]=[CH:15][C:5]([O:6][C:7]2[CH:14]=[CH:13][C:10]([CH:11]=O)=[CH:9][CH:8]=2)=[C:4]([Cl:17])[CH:3]=1.[NH2:18][OH:19]>CN(C=O)C>[Br:1][C:2]1[CH:16]=[CH:15][C:5]([O:6][C:7]2[CH:14]=[CH:13][C:10]([CH:11]=[N:18][OH:19])=[CH:9][CH:8]=2)=[C:4]([Cl:17])[CH:3]=1

Participants

4

Reactant 2

HCID 787HydroxylamineHCID 288931534-(4-Bromo-2-chloro-phenoxy)-benzaldehyde

Product 1

HCID 866588184-(4-Bromo-2-chloro-phenoxy)-benzaldehyde-oxime

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

20 mg (0.06 mmol) of 4-(4-bromo-2-chloro-phenoxy)-benzaldehyde were stirred with 20 μL (0.33 mmol) of hydroxylamine solution (50% in water) in 2 mL f DMF at 80° C. for 1 h. The reaction mixture was purified by chromatography (reversed phase).

Workup

  1. customThe reaction mixture was purified by chromatography (reversed phase)

Sources & evidence

ORD record
ord-64fa39e5ed964d61b5f7065c943dcdbc
Source dataset
uspto-grants-2014_12
Patent number
US08916589B2

Reaction notes

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