HRID1406503

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7972

4-Methylmorpholine

C5H11NO

结构：CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F

HCID2733207

O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate

C11H16BF4N5O

HCID24191928

4,4-Dimethylcyclohexan-1-amine--hydrogen chloride (1/1)

C8H18ClN

结构：Cn1c(Nc2c(Cl)cccc2Cl)nc2ccc(C(=O)O)cc21

HCID68519287

未命名化合物

PRODUCTS

生成物

结构：Cn1c(Nc2c(Cl)cccc2Cl)nc2cc(C(=O)NC3CCC(C)(C)CC3)ccc21

HCID58562300

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

Prepared analogously to example 3c from 2-(2,6-dichloro-phenylamino)-1-methyl-1H-benzimidazole-6-carboxylic acid, 4,4-dimethyl-cyclohexylamine hydrochloride, TBTU and NMM in DMF; mp: 189-190° C., Rf value: 0.56 (silica gel; petrol ether/ethyl acetate=2:1).