Methylamine → HCID 59529818, compound

HRID 1406524Notes

Reaction equation

HRID 1406524 reaction equation

[CH2:1]([O:3][C:4](=[O:16])[C:5]1[CH:10]=[C:9]([N+:11]([O-:13])=[O:12])[C:8](F)=[CH:7][C:6]=1[F:15])[CH3:2].[CH3:17][NH2:18]>C1COCC1>[CH2:1]([O:3][C:4](=[O:16])[C:5]1[CH:10]=[C:9]([N+:11]([O-:13])=[O:12])[C:8]([NH:18][CH3:17])=[CH:7][C:6]=1[F:15])[CH3:2]

Participants

4

Reactant 2

HCID 6329Methylamine

HCID 22330120Ethyl 2,4-difluoro-5-nitrobenzoate

Product 1

HCID 59529818HCID 59529818, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Prepared analogously to example 156b from 2,4-difluoro-5-nitro-benzoic acid ethyl ester and 2 M methylamine (solution in THF) in THF.

Sources & evidence

ORD record: ord-80443c2b27844accaa30204349fc74af
Source dataset: uspto-grants-2014_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08916599B2

Reaction notes

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