Hydrochloric Acid → Diethyl 2-(2,6-difluoro-4-methoxyphenyl)malonate
Reaction equation
[C:1]([CH2:2][C:3](=[O:4])[O:5][CH2:6][CH3:7])(=[O:8])[O:9][CH2:10][CH3:11].[CH2:28]1[O:29][CH2:30][CH2:31][O:32][CH2:33]1.[ClH:25].[Cu:26][Br:27].[F:14][c:15]1[c:16]([Br:24])[c:17]([F:23])[cH:18][c:19]([O:21][CH3:22])[cH:20]1.[H-:12].[Na+:13]>>[C:1]([CH:2]([C:3](=[O:4])[O:5][CH2:6][CH3:7])[c:16]1[c:15]([F:14])[cH:20][c:19]([O:21][CH3:22])[cH:18][c:17]1[F:23])(=[O:8])[O:9][CH2:10][CH3:11]Participants
8
Sources & evidence
- ORD record
- ord-6dfdf0b1dbb3451795236b1e1a43cdaa
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…