Hydrochloric Acid → HCID 57183577, compound

HRID 1413060Notes

Reaction equation

HRID 1413060 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]1[C:12](=[N:13][CH:14](Cl)[C:15]([Br:19])([Br:18])[CH2:16][Cl:17])[C:11](=[O:21])[N:10]([CH3:22])[C:9]1=[O:23].[Br:24][C:25]1[CH:31]=[CH:30][CH:29]=[CH:28][C:26]=1[NH2:27].C(N(CC)CC)C.Cl>C(#N)C.C(OCC)C>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]1[C:12](=[N:13][CH:14]([NH:27][C:26]2[CH:28]=[CH:29][CH:30]=[CH:31][C:25]=2[Br:24])[C:15]([Br:19])([Br:18])[CH2:16][Cl:17])[C:11](=[O:21])[N:10]([CH3:22])[C:9]1=[O:23]

Participants

7

Reactant 4

HCID 313Hydrochloric AcidHCID 8471TriethylamineHCID 119922-BromoanilineHCID 57235154HCID 57235154, compound

Product 1

HCID 57183577HCID 57183577, compound

Reagents, catalysts & solvents 2

HCID 3283Diethyl EtherSolventHCID 6342AcetonitrileSolvent

Procedure

In this example 0.02 mol of 1-(2-fluorophenyl)-3-methyl-5-(1,3-dichloro-2,2-dibromopropyl)imino-1,3-diazolidine-2,4-dione is dissolved in 20 ml of acetonitrile and then 0.02 of mol of 2-bromoaniline is added. After about 10 minutes, triethylamine is added to neutralize the byproduct HCl produced by the reaction. The mixture is stirred for five hours and 20 ml of ethyl ether is then added. The mixture is filtered and the filtrate evaporated under high vacuum affording 1-(2-fluorophenyl)-3-methyl-5-(1-2'-bromophenylamino-2,2,-dibromo-3-chloropropyl)imino-1,3-diazolidine-2,4-dione.

Workup

  1. customproduced by the reaction
  2. filtrationThe mixture is filtered
  3. customthe filtrate evaporated under high vacuum

Sources & evidence

ORD record
ord-9365866a99da4ad5aaa7d0e949c1e91d
Source dataset
uspto-grants-1981_02
Patent number
US04248620

Reaction notes

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