1,2-Dibromoethane → HCID 21487980, compound

HRID 1414615Notes

Reaction equation

HRID 1414615 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]3[CH:16]=[CH:15][CH:14]=[CH:13][C:11]=3[CH:12]=2)=[CH:4][CH:3]=1.[Br:17][CH2:18][CH2:19]Br.C(=O)([O-])[O-].[K+].[K+]>CCC(=O)CC>[Br:17][CH2:18][CH2:19][O:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]3[CH:16]=[CH:15][CH:14]=[CH:13][C:11]=3[CH:12]=2)=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 78391,2-DibromoethaneHCID 11430Potassium CarbonateHCID 101251634-(1-Benzofuran-2-yl)phenol

Product 1

HCID 21487980HCID 21487980, compound

Reagents, catalysts & solvents 1

HCID 7288Ethyl ketoneSolvent

Procedure

A mixture of 10.5 g. (0.05 mol.) of 2-p-hydroxyphenylbenzofuran and 47 g. (0.25 mol.) of 1,2-dibromoethane in 200 ml. of 3-pentanone containing 46 g. (0.3 mol.) of potassium carbonate was heated at 100° for 12 hours. The mixture was filtered while hot and the solid remaining was washed with hot acetone. The combined filtrate and washings were concentrated to give 2-[4'-(2-bromoethoxy)phenyl]benzofuran.

Workup

  1. additionA mixture of 10.5 g
  2. filtrationThe mixture was filtered while hot and the solid
  3. washremaining was washed with hot acetone
  4. concentrationThe combined filtrate and washings were concentrated

Sources & evidence

ORD record
ord-533545304e0a46c2a6fe7388c120d843
Source dataset
uspto-grants-1977_01
Patent number
US04001426

Reaction notes

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