反应详情

2-Amino-4-chloro-6-hydroxy-5-nitropyrimidine (4 g), 3-methylbutylamine (1.8 g) and triethylamine (6 ml) were heated at reflux for 5 h then left stirring overnight at room temperature in ethanol. The precipitate was filtered and washed with water and air dried to yield the title compound as a yellow solid.

1. temperatureat reflux for 5 h
2. waitthen left
3. filtrationThe precipitate was filtered
4. washwashed with water and air
5. customdried