Hydrochloric Acid → tert-butyl N-[1-[[1-[dimethylamino(methyl)amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-3-naphthalen-2-yl-1-oxopropan-2-yl]-N-methylcarbamate

HRID 142243Notes

Reaction equation

HRID 142243 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]([CH3:9])[CH:10]([C:11](=[O:12])[OH:13])[CH2:14][c:15]1[cH:16][c:17]2[cH:18][cH:19][cH:20][cH:21][c:22]2[cH:23][cH:24]1.[CH2:36]([N:37]=[C:38]=[N:39][CH2:40][CH2:41][CH2:42][N:43]([CH3:44])[CH3:45])[CH3:46].[CH2:73]([Cl:74])[Cl:75].[CH3:47][N:48]([N:49]([C:50]([CH:51]([CH2:52][c:53]1[cH:54][cH:55][cH:56][cH:57][cH:58]1)[NH:59][CH3:60])=[O:61])[CH3:62])[CH3:63].[CH:64]([N:65]([CH:66]([CH3:67])[CH3:68])[CH2:69][CH3:70])([CH3:71])[CH3:72].[ClH:35].[OH:25][n:26]1[c:27]2[n:28][cH:29][cH:30][cH:31][c:32]2[n:33][n:34]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]([CH3:9])[CH:10]([C:11](=[O:13])[N:59]([CH:51]([C:50]([N:49]([N:48]([CH3:47])[CH3:63])[CH3:62])=[O:61])[CH2:52][c:53]1[cH:54][cH:55][cH:56][cH:57][cH:58]1)[CH3:60])[CH2:14][c:15]1[cH:16][c:17]2[cH:18][cH:19][cH:20][cH:21][c:22]2[cH:23][cH:24]1

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 81531DiisopropylethylamineHCID 181649HOAtHCID 223269722-[Methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]-3-naphthalen-2-ylpropanoic acidHCID 70298246N,N',N'-trimethyl-2-(methylamino)-3-phenylpropanehydrazide

Product 1

HCID 57272896tert-butyl N-[1-[[1-[dimethylamino(methyl)amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-3-naphthalen-2-yl-1-oxopropan-2-yl]-N-methylcarbamate

Sources & evidence

ORD record
ord-2cce08c013264556bbc810e897b24375
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…