反应详情

To a suspension of 10 g (47.57 mmol) 5-hydroxy-isophthalic acid dimethyl ester and 9.86 g (71.36 mmol) K2CO3 in 50 ml DMF is added dropwise 7.67 ml (95.1 mmol) ethyl iodide. After the addition the mixture is stirred for 5 h, diluted with water and extracted with TBME. The organic phase is washed with water, dried with sodium sulfate and evaporated to give the title compound.

1. additionAfter the addition the mixture
2. extractionextracted with TBME
3. washThe organic phase is washed with water
4. dry with materialdried with sodium sulfate
5. customevaporated