反应详情

A mixture of 9.9 g of 2B, 25 ml of dimethylformamide, 11 g of 1A and 2 g of triethylamine (catalyst) was heated in a steam bath for 24 hours. The resulting mixture was diluted with ether and water, and phase-separated. The ether phase was washed with water, and dried (MgSO4), and the solvent was evaporated. The residue was triturated with ether. The residual off-white solid was 2, m.p.: 118°-120° C.

1. temperaturewas heated in a steam bath for 24 hours
2. customphase-separated
3. washThe ether phase was washed with water
4. dry with materialdried (MgSO4)
5. customthe solvent was evaporated
6. customThe residue was triturated with ether