Hydrochloric Acid → Tert-butyl 2-(methoxy(methyl)carbamoyl)morpholine-4-carboxylate

HRID 145263Notes

Reaction equation

HRID 145263 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([C:14](=[O:15])[OH:16])[O:11][CH2:12][CH2:13]1.[CH3:18][NH:19][O:20][CH3:21].[CH:22]([N:23]([CH2:24][CH3:25])[CH:26]([CH3:27])[CH3:28])([CH3:29])[CH3:30].[ClH:17].[O:65]=[CH:66][N:67]([CH3:68])[CH3:69].[OH2:70].[OH:55][n:56]1[c:57]2[c:58]([cH:59][cH:60][cH:61][cH:62]2)[n:63][n:64]1.[P-:31]([F:32])([F:33])([F:34])([F:35])([F:36])[F:37].[n:38]1([O:39][C:40]([N:41]([CH3:42])[CH3:43])=[N+:44]([CH3:45])[CH3:46])[c:47]2[cH:48][cH:49][cH:50][cH:51][c:52]2[n:53][n:54]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([C:14](=[O:16])[N:19]([CH3:18])[O:20][CH3:21])[O:11][CH2:12][CH2:13]1

Participants

10

Reactant 9

HCID 313Hydrochloric AcidHCID 962WaterHCID 6228DimethylformamideHCID 9886HexafluorophosphateHCID 14232N,O-DimethylhydroxylamineHCID 757711-HydroxybenzotriazoleHCID 81531DiisopropylethylamineHCID 130500O-benzotriazol-1-yl-tetramethyluroniumHCID 27559654-((Tert-butoxy)carbonyl)morpholine-2-carboxylic acid

Product 1

HCID 57449675Tert-butyl 2-(methoxy(methyl)carbamoyl)morpholine-4-carboxylate

Sources & evidence

ORD record
ord-cac0c1a6163f432fbbd91f636c419af6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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