Water → HCID 178495096, compound

HRID 1462604Notes

Reaction equation

HRID 1462604 reaction equation
[CH3:1][O:2][CH2:3][CH:4]([CH2:8][C:9]([OH:11])=[O:10])[C:5](O)=[O:6].[Cl:12][C:13]1[CH:14]=[C:15]([CH:17]=[C:18]([Cl:20])[CH:19]=1)[NH2:16].C(N(CC)CC)C.O>C1(C)C(C)=CC=CC=1>[Cl:12][C:13]1[CH:14]=[C:15]([N:16]=[C:5]([OH:6])[CH:4]([CH2:3][O:2][CH3:1])[CH2:8][C:9]([OH:11])=[O:10])[CH:17]=[C:18]([Cl:20])[CH:19]=1

Participants

6

Reactant 4

HCID 962WaterHCID 8471TriethylamineHCID 122813,5-DichloroanilineHCID 415626481949-89-5

Product 1

HCID 178495096HCID 178495096, compound

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

150 g of 2-methoxymethylsuccinic acid, 150g of 3,5-dichloroaniline and 0.5 g of triethylamine are heated under reflux, for four hours, in 1.5 liters of xylene, and the water formed is separated off by means of a water separator. The solvent is then drawn off. 250 g of end product are obtained in crystalline form.

Workup

  1. customis separated off by means of a water separator
  2. custom250 g of end product are obtained in crystalline form

Sources & evidence

ORD record
ord-559702152d9d4d1a95833bbc09cc487b
Source dataset
uspto-grants-1984_07
Patent number
US04460782

Reaction notes

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