N,N,N',N'-Tetramethylazodicarboxamide → 2-Methyl-1,3,4,8-tetrahydro-2H-[1,4]oxazepino[6,7-e]indole

HRID 147817Notes

Reaction equation

HRID 147817 reaction equation
[CH2:48]1[O:49][CH2:50][CH2:51][CH2:52]1.[N:17]([C:18]([N:19]([CH3:20])[CH3:21])=[O:22])=[N:23][C:24]([N:25]([CH3:26])[CH3:27])=[O:28].[OH:1][CH2:2][CH2:3][N:4]([CH3:5])[CH2:6][c:7]1[c:8]2[cH:9][cH:10][nH:11][c:12]2[cH:13][cH:14][c:15]1[OH:16].[c:29]1([P:30]([c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[cH:43][cH:44][cH:45][cH:46][cH:47]1>>[CH2:2]1[CH2:3][N:4]([CH3:5])[CH2:6][c:7]2[c:8]3[cH:9][cH:10][nH:11][c:12]3[cH:13][cH:14][c:15]2[O:16]1

Participants

5

Reactant 4

HCID 4278N,N,N',N'-TetramethylazodicarboxamideHCID 8028TetrahydrofuranHCID 11776TriphenylphosphineHCID 672405814-{[(2-Hydroxy-ethyl)-methyl-amino]-methyl}-1H-indol-5-ol

Product 1

HCID 672416342-Methyl-1,3,4,8-tetrahydro-2H-[1,4]oxazepino[6,7-e]indole

Sources & evidence

ORD record
ord-6c7a97a6b5f9416380c71ddfeb15c8c9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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