Cyanide → 6-Cyano-2-(2-fluoro-4-trimethylsilanyl-phenylamino)-nicotinic acid methyl ester
Reaction equation
[C-:29]#[N:30].[C-:32]#[N:33].[CH3:1][O:2][C:3]([c:4]1[c:5]([NH:11][c:12]2[c:13]([F:22])[cH:14][c:15]([Si:18]([CH3:19])([CH3:20])[CH3:21])[cH:16][cH:17]2)[n:6][c:7]([Cl:10])[cH:8][cH:9]1)=[O:23].[CH3:24][N:25]([CH3:26])[CH:27]=[O:28].[Zn+2:31].[cH:34]1[cH:35][cH:36][c:37]([P:38]([Pd:39]([P:40]([c:41]2[cH:42][cH:43][cH:44][cH:45][cH:46]2)([c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)[c:53]2[cH:54][cH:55][cH:56][cH:57][cH:58]2)([P:59]([c:60]2[cH:61][cH:62][cH:63][cH:64][cH:65]2)([c:66]2[cH:67][cH:68][cH:69][cH:70][cH:71]2)[c:72]2[cH:73][cH:74][cH:75][cH:76][cH:77]2)[P:78]([c:79]2[cH:80][cH:81][cH:82][cH:83][cH:84]2)([c:85]2[cH:86][cH:87][cH:88][cH:89][cH:90]2)[c:91]2[cH:92][cH:93][cH:94][cH:95][cH:96]2)([c:97]2[cH:98][cH:99][cH:100][cH:101][cH:102]2)[c:103]2[cH:104][cH:105][cH:106][cH:107][cH:108]2)[cH:109][cH:110]1>>[CH3:1][O:2][C:3]([c:4]1[c:5]([NH:11][c:12]2[c:13]([F:22])[cH:14][c:15]([Si:18]([CH3:19])([CH3:20])[CH3:21])[cH:16][cH:17]2)[n:6][c:7]([C:24]#[N:25])[cH:8][cH:9]1)=[O:23]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-a7c420c8909d40a68d93c31146ee1121
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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