Iodoethane → Ethyl 2-formylbenzoate

HRID 1489103Notes

Reaction equation

[C:1]([C:5]1[CH:12]=[CH:11][CH:10]=[CH:9][C:6]=1[CH:7]=[O:8])([O:3][CH3:4])=[O:2].[C:13](C1C=CC=CC=1C=O)(O)=O.ICC.C([O-])([O-])=O.[K+].[K+]>>[C:1]([C:5]1[CH:12]=[CH:11][CH:10]=[CH:9][C:6]=1[CH:7]=[O:8])([O:3][CH2:4][CH3:13])=[O:2]

Participants

Reactant 4

HCID 6340Iodoethane

HCID 8406Phthalaldehydic acid

HCID 11430Potassium Carbonate

HCID 243003Methyl 2-formylbenzoate2×

Product 1

HCID 10943020Ethyl 2-formylbenzoate

Procedure

Using the same procedure as for the preparation of 2-carbomethoxybenzaldehyde (Compound 43), but instead using 5.0 g (33 mmol) of 2-carboxybenzaldehyde, 23.4 g (150 mmol) of iodoethane and 13.8 g (100 mmol) of K2CO3 gave the title compound as a clear colorless oil.

Sources & evidence

ORD record: ord-4e6eba2c1a244593a6ecb9075c7f9fcb
Source dataset: uspto-grants-1997_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05677320

Reaction notes

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