HCID 12735200, compound → HCID 178422404, compound
Reaction equation
Cc1cccc2c1N(C)CCC2>B1Oc2ccccc2O1.CC(C)(O)C(C)(C)O.CCN(CC)CC.Cc1ccccc1.Fc1c(F)c(F)c(B(c2c(F)c(F)c(F)c(F)c2F)c2c(F)c(F)c(F)c(F)c2F)c(F)c1F>Cc1cc(B2OC(C)(C)C(C)(C)O2)cc2c1N(C)CCC2Participants
7
Conditions
- Temperature
- 120 °C
Procedure
Prepared from 1,8-dimethyl-1,2,3,4-tetrahydroquinoline (1l, 32.2 mg, 0.200 mmol, 1.00 equiv) and catBH (36.0 mg, 0.300 mmol, 1.50 equiv) according to GP 1. The title compound was purified by flash column chromatography using cyclohexane/EtOAc/Et3N (30/1/1) as eluent to afford 3l (43.1 mg, 75%) as a white solid
Sources & evidence
- ORD record
- ord-a5383b6d58804592a987d6287c524a14
- Source dataset
- Borylation dataset from Roche
Reaction notes
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