Triethylamine → HCID 118380271, compound

HRID 1504570Notes

Reaction equation

HRID 1504570 reaction equation
[C:1]([N:8]([CH2:12][CH2:13][OH:14])[CH2:9][CH2:10][OH:11])([O:3][C:4]([CH3:7])([CH3:6])[CH3:5])=[O:2].C(N(CC)CC)C.Cl[C:23](Cl)([O:25]C(=O)OC(Cl)(Cl)Cl)Cl>ClCCl>[C:1]([N:8]1[CH2:9][CH2:10][O:11][C:23](=[O:25])[O:14][CH2:13][CH2:12]1)([O:3][C:4]([CH3:6])([CH3:7])[CH3:5])=[O:2]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 94429TriphosgeneHCID 4360601N-Boc-diethanolamine

Product 1

HCID 118380271HCID 118380271, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The procedure of Example 1 was followed using N-boc diethanolamine (3 g, 14.6 mmol), triethylamine (4.1 mL, 29.2 mmol), dry dichloromethane (100 mL) and triphosgene (1.4 g, 4.9 mmol). The filtrate was concentrated yielding only oligomeric compounds.

Workup

  1. concentrationThe filtrate was concentrated
  2. customyielding only oligomeric compounds

Sources & evidence

ORD record
ord-e881160028974952840763b6267931ac
Source dataset
uspto-grants-2015_12
Patent number
US09215876B2

Reaction notes

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