Chloride → ethyl (2RS,3RS)-3-(3-fluorophenyl)-3-hydroxy-2-((4-(trifluoromethyl)phenyl)methyl)propionate
Reaction equation
[BH4-:1].[CH3:30][CH2:31][O:32][CH2:33][CH3:34].[Cl-:35].[Cl-:37].[ClH:29].[F:3][c:4]1[cH:5][c:6]([C:10]([CH:11]([C:12](=[O:13])[O:14][CH2:15][CH3:16])[CH2:17][c:18]2[cH:19][cH:20][c:21]([C:24]([F:25])([F:26])[F:27])[cH:22][cH:23]2)=[O:28])[cH:7][cH:8][cH:9]1.[Na+:2].[Zn+2:36]>>[F:3][c:4]1[cH:5][c:6]([CH:10]([CH:11]([C:12](=[O:13])[O:14][CH2:15][CH3:16])[CH2:17][c:18]2[cH:19][cH:20][c:21]([C:24]([F:25])([F:26])[F:27])[cH:22][cH:23]2)[OH:28])[cH:7][cH:8][cH:9]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-a1672ea40d5f40beadbed3172b50d071
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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