反应详情

温度

70 °C

To a solution of reactant 3 in CH3CN was added reactant 2 and POCl3. The mixture was stirred at 70° C. overnight under. N2. TLC showed starting material was consumed. The mixture was then poured into NaHCO3 (aq) carefully and the precipitate collected. The dried sample was confirmed as desired product 2-chloro-4-(5-chlorothiophen-2-yl)-6-methyl-1,3,5-triazine 4.

1. customwas consumed
2. additionThe mixture was then poured into NaHCO3 (aq) carefully
3. customthe precipitate collected