反应详情

温度

0 °C

To a solution of compound 4 and Et3N in DCM was added TsCl dropwise. The resulting mixture was stirred at 0° C. for 30 min. The solid was filtered and the solvent was removed. The residue was purified by column chromatography to give compound 5.

1. filtrationThe solid was filtered
2. customthe solvent was removed
3. customThe residue was purified by column chromatography