Hydrogen Bromide → 7-(5-Acetamidomethyl-2-isoindolinyl)-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid
Reaction equation
[BrH:21].[C:22]([CH3:23])(=[O:24])[NH:25][CH2:26][c:27]1[cH:28][c:29]2[c:33]([cH:34][cH:35]1)[CH2:32][NH:31][CH2:30]2.[CH2:36]1[CH2:37][CH2:38][C:39]2=[N:44][CH2:43][CH2:42][CH2:41][N:40]2[CH2:45][CH2:46]1.[CH:1]1([n:4]2[cH:5][c:6]([C:18](=[O:19])[OH:20])[c:7](=[O:17])[c:8]3[cH:9][c:10]([F:16])[c:11]([F:15])[c:12]([F:14])[c:13]23)[CH2:2][CH2:3]1.[O:47]=[CH:48][N:49]([CH3:50])[CH3:51]>>[CH:1]1([n:4]2[cH:5][c:6]([C:18](=[O:19])[OH:20])[c:7](=[O:17])[c:8]3[cH:9][c:10]([F:16])[c:11]([N:31]4[CH2:30][c:29]5[cH:28][c:27]([CH2:26][NH:25][C:22]([CH3:23])=[O:24])[cH:35][cH:34][c:33]5[CH2:32]4)[c:12]([F:14])[c:13]23)[CH2:2][CH2:3]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-65b539db923248ae929b92fe50f326b5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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