反应详情

A mixture of 1-(3-tert-butoxy-4-nitrophenyl)-3,4-difluoro-1H-pyrrole (8.30 g), TFA (30 mL) and THF (60 mL) was heated under reflux for 3 hr. The reaction mixture was concentrated under reduced pressure, and the residue was washed with hexane/ethyl acetate (10/1) to give the title compound (6.43 g).

1. temperaturewas heated
2. temperatureunder reflux for 3 hr
3. concentrationThe reaction mixture was concentrated under reduced pressure
4. washthe residue was washed with hexane/ethyl acetate (10/1)