m-Chloroperbenzoic acid → HCID 68014666, compound

HRID 1528080Notes

Reaction equation

HRID 1528080 reaction equation
ClC1C=CC=C(C(OO)=[O:9])C=1.[CH3:12][O:13][C:14]1[C:15](=[O:37])[C:16]([C:26]2[N:30]([C:31]3[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=3)[N:29]=[CH:28][CH:27]=2)=[N:17][N:18]([C:20]2[CH:21]=[N:22][CH:23]=[CH:24][CH:25]=2)[CH:19]=1>CN(C=O)C>[CH3:12][O:13][C:14]1[C:15](=[O:37])[C:16]([C:26]2[N:30]([C:31]3[CH:32]=[CH:33][CH:34]=[CH:35][CH:36]=3)[N:29]=[CH:28][CH:27]=2)=[N:17][N:18]([C:20]2[CH:21]=[N+:22]([O-:9])[CH:23]=[CH:24][CH:25]=2)[CH:19]=1

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 58072317HCID 58072317, compound

Product 1

HCID 68014666HCID 68014666, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent2×

Procedure

To a DMF solution (2.0 ml) of m-chloroperbenzoic acid (0.398 mg) was added a DMF solution (12.0 ml) of 5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)-1-(pyridin-3-yl)pyridazin-4(1H)-one at 0° C., and the mixture was stirred overnight at room temperature. The precipitated solid was collected by filtration to give the title compound (168 mg).

Workup

  1. filtrationThe precipitated solid was collected by filtration

Sources & evidence

ORD record
ord-5bc866aa835e4ce3b585ddfad94e45b8
Source dataset
uspto-grants-2015_07
Patent number
US09090586B2

Reaction notes

Loading…