Tetrahydrofuran → 1-(4-Ethylpiperazin-1-yl)-3-[(3-pyridyl)hydroxymethyl]isoquinoline
Reaction equation
[CH2:1]([CH3:2])[N:3]1[CH2:4][CH2:5][N:6]([c:9]2[n:10][c:11]([Br:19])[cH:12][c:13]3[cH:14][cH:15][cH:16][cH:17][c:18]23)[CH2:7][CH2:8]1.[CH3:20][CH2:21][CH2:22][CH2:23][Li:24].[CH3:38][CH2:39][O:40][C:41](=[O:42])[CH3:43].[CH:25](=[O:26])[c:27]1[cH:28][n:29][cH:30][cH:31][cH:32]1.[O:33]1[CH2:34][CH2:35][CH2:36][CH2:37]1>>[CH2:1]([CH3:2])[N:3]1[CH2:4][CH2:5][N:6]([c:9]2[n:10][c:11]([CH:25]([OH:26])[c:27]3[cH:28][n:29][cH:30][cH:31][cH:32]3)[cH:12][c:13]3[cH:14][cH:15][cH:16][cH:17][c:18]23)[CH2:7][CH2:8]1Participants
6
Sources & evidence
- ORD record
- ord-a1aa054070004ef7a3f688255e4a5a20
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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