Oxalyl chloride → 1378828-50-2

HRID 1532712Notes

Reaction equation

HRID 1532712 reaction equation
C(Cl)(=O)C([Cl:4])=O.[Cl:7][CH2:8][CH2:9][CH2:10][C:11]([CH3:16])([CH3:15])[C:12](O)=[O:13]>CN(C=O)C.C(Cl)(Cl)Cl>[Cl:7][CH2:8][CH2:9][CH2:10][C:11]([CH3:16])([CH3:15])[C:12]([Cl:4])=[O:13]

Participants

5

Reactant 2

HCID 65578Oxalyl chlorideHCID 15688742HCID 15688742, compound

Product 1

HCID 544870051378828-50-2

Reagents, catalysts & solvents 2

HCID 6228DimethylformamideCatalystHCID 6212ChloroformSolvent

Procedure

Oxalyl chloride (888 mg, 7 mmols) was added to a chloroform (10 ml) solution of the resulting carboxylic acid (0.9 g, 5 mmols) and DMF (catalytic amount, 1 drop), and stirred at room temperature for 1 hour. The reaction mixture was concentrated to obtain 5-chloro-2,2-dimethylpentanoic acid chloride.

Workup

  1. concentrationThe reaction mixture was concentrated

Sources & evidence

ORD record
ord-67da03d656d64f06bcfb40b2f92742d8
Source dataset
uspto-grants-2001_03
Patent number
US06204278B1

Reaction notes

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