Hydrochloric Acid → N-[2-(1,2,3,7,8,9-hexahydro-2-oxoindeno[5,4-b][1,4]oxazin-9-yl)ethyl]propionamide

HRID 153296Notes

Reaction equation

HRID 153296 reaction equation
[CH2:2]([N:3]=[C:4]=[N:5][CH2:6][CH2:7][CH2:8][N:9]([CH3:10])[CH3:11])[CH3:12].[CH3:24][CH2:25][C:26]([OH:27])=[O:28].[CH3:46][N:47]([CH3:48])[CH:49]=[O:50].[ClH:1].[NH2:29][CH2:30][CH2:31][CH:32]1[CH2:33][CH2:34][c:35]2[cH:36][cH:37][c:38]3[c:43]([c:44]21)[NH:42][C:41](=[O:45])[CH2:40][O:39]3.[OH2:13].[OH2:51].[OH:14][n:15]1[c:16]2[cH:17][cH:18][cH:19][cH:20][c:21]2[n:22][n:23]1>>[CH3:24][CH2:25][C:26](=[O:28])[NH:29][CH2:30][CH2:31][CH:32]1[CH2:33][CH2:34][c:35]2[cH:36][cH:37][c:38]3[c:43]([c:44]21)[NH:42][C:41](=[O:45])[CH2:40][O:39]3

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 962Water2×HCID 1032Propionic AcidHCID 6228DimethylformamideHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 757711-HydroxybenzotriazoleHCID 111281719-(2-aminoethyl)-1,7,8,9-tetrahydro-indeno[5,4-b][1,4]oxazin-2(3H)-one

Product 1

HCID 11011664N-[2-(1,2,3,7,8,9-hexahydro-2-oxoindeno[5,4-b][1,4]oxazin-9-yl)ethyl]propionamide

Sources & evidence

ORD record
ord-444d103e74ca4b2cb69a1bdc7363a5cd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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