Potassium Iodide → HCID 15030095, compound

HRID 1533909Notes

Reaction equation

HRID 1533909 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[N:7]1[CH2:12][CH2:11][NH:10][CH2:9][CH2:8]1.Cl[CH2:14][CH2:15][CH:16]1[O:20][C:19](=[O:21])[N:18]([CH3:22])[CH2:17]1.C(=O)([O-])[O-].[Na+].[Na+].[I-].[K+]>C(O)CCC.CC(O)C>[CH3:22][N:18]1[CH2:17][CH:16]([CH2:15][CH2:14][N:10]2[CH2:9][CH2:8][N:7]([C:2]3[CH:3]=[CH:4][CH:5]=[CH:6][N:1]=3)[CH2:12][CH2:11]2)[O:20][C:19]1=[O:21]

Participants

7

Reactant 4

HCID 4875Potassium IodideHCID 10340Sodium CarbonateHCID 944591-(2-Pyridyl)piperazineHCID 146987465-(2-Chloro-ethyl)-3-methyl-oxazolidin-2-one

Product 1

HCID 15030095HCID 15030095, compoundYield 75.8%

Reagents, catalysts & solvents 2

HCID 2631-ButanolSolventHCID 3776IsopropanolSolvent

Procedure

This compound was prepared according to the procedure of Example 2. A mixture of 4.1 g (0.025 mol) of 1-(2-pyridinyl)piperazine, 4.1 g (0.025 mol) of 5-(2-chloroethyl)-3-methyl-2-oxazolidinone, 8.0 g (0.075 mol) of anhydrous sodium carbonate and 0.4 g of potassium iodide in 150 mL of 1-butanol gave 5.5 g (75%) of white solid, mp 107.5°-109° C. (2-propanol).

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-5a2f0499479e4b82b6011f132ad902e4
Source dataset
uspto-grants-1992_02
Patent number
US05086055

Reaction notes

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