反应详情

温度

-20 °C

A solution of 0.1 mol of N-formylpiperidine in 10 ml of THF is added dropwise at -60° C. to the solution of 4-ethoxy-2,3-difluorophenyllithium in THF/hexane prepared according to 1b). The mixture is then warmed to -20° C. in the course of 1 hour. Customary working up (recrystallization from petroleum ether (boiling range 40°-60° C.) gives colourless crystals, m.p. 70° C.

1. customprepared
2. customrecrystallization from petroleum ether (boiling range 40°-60° C.)
3. customgives colourless crystals, m.p. 70° C.