Dimethylformamide → 2-Hydroxyethyl 6-(4-cyano-2-methylsulfonylphenyl)-4-methyl-2-oxo-3-[3-(trifluoromethyl)phenyl]-1,6-dihydropyrimidine-5-carboxylate
Reaction equation
[Br:34][CH2:35][CH2:36][OH:37].[C:1](#[N:2])[c:3]1[cH:4][c:5]([S:30](=[O:31])(=[O:32])[CH3:33])[c:6]([CH:9]2[NH:10][C:11](=[O:29])[N:12]([c:19]3[cH:20][c:21]([C:25]([F:26])([F:27])[F:28])[cH:22][cH:23][cH:24]3)[C:13]([CH3:18])=[C:14]2[C:15](=[O:16])[OH:17])[cH:7][cH:8]1.[CH3:38][CH2:39][N:40]([CH2:41][CH3:42])[CH2:43][CH3:44].[O:45]=[CH:46][N:47]([CH3:48])[CH3:49]>>[C:1](#[N:2])[c:3]1[cH:4][c:5]([S:30](=[O:31])(=[O:32])[CH3:33])[c:6]([CH:9]2[NH:10][C:11](=[O:29])[N:12]([c:19]3[cH:20][c:21]([C:25]([F:26])([F:27])[F:28])[cH:22][cH:23][cH:24]3)[C:13]([CH3:18])=[C:14]2[C:15](=[O:16])[O:17][CH2:35][CH2:36][OH:37])[cH:7][cH:8]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-dbf937bbc1bc4bca88d020c8446e8685
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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