Chloride → Ethyl 3-oxo-3-(thiophen-2-yl)propanoate

HRID 1539386Notes

Reaction equation

HRID 1539386 reaction equation
[C:9]([n:10]1[cH:11][cH:12][n:13][cH:14]1)([n:15]1[cH:16][cH:17][n:18][cH:19]1)=[O:20].[CH2:24]([CH3:25])[O:26][C:27]([CH2:28][C:29]([O-:30])=[O:31])=[O:32].[Cl-:21].[Cl-:23].[Mg+2:22].[O:33]1[CH2:34][CH2:35][CH2:36][CH2:37]1.[OH2:38].[s:1]1[c:2]([C:6](=[O:7])[OH:8])[cH:3][cH:4][cH:5]1>>[s:1]1[c:2]([C:6](=[O:8])[CH2:28][C:27]([O:26][CH2:24][CH3:25])=[O:32])[cH:3][cH:4][cH:5]1

Participants

8

Reactant 7

HCID 312Chloride2×HCID 888Magnesium CationHCID 962WaterHCID 8028TetrahydrofuranHCID 107002-Thiophenecarboxylic acidHCID 682631,1'-CarbonyldiimidazoleHCID 3595298Propanedioic acid, monoethyl ester

Product 1

HCID 255159Ethyl 3-oxo-3-(thiophen-2-yl)propanoate

Sources & evidence

ORD record
ord-ff71135002f1413295e84905e958e638
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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