Potassium Cation → 1-[5-chloro-3-(2-methoxyphenyl)-1-[4-methoxy-2-(trifluoromethoxy)phenyl]sulfonyl-2-oxoindol-3-yl]-4-fluoro-N,N-dimethylpyrrolidine-2-carboxamide

HRID 1539519Notes

Reaction equation

HRID 1539519 reaction equation
[CH2:69]1[O:70][CH2:71][CH2:72][CH2:73]1.[CH3:12][Si:13]([N-:14][Si:15]([CH3:16])([CH3:17])[CH3:18])([CH3:19])[CH3:20].[CH3:74][CH2:75][O:76][C:77]([CH3:78])=[O:79].[Cl:22][C:23]1([c:50]2[c:51]([O:56][CH3:57])[cH:52][cH:53][cH:54][cH:55]2)[C:24](=[O:49])[N:25]([S:33](=[O:34])(=[O:35])[c:36]2[c:37]([O:44][C:45]([F:46])([F:47])[F:48])[cH:38][c:39]([O:42][CH3:43])[cH:40][cH:41]2)[c:26]2[cH:27][cH:28][c:29]([Cl:32])[cH:30][c:31]21.[F:1][CH:2]1[CH2:3][CH:4]([C:7](=[O:8])[N:9]([CH3:10])[CH3:11])[NH:5][CH2:6]1.[K+:58].[K+:59].[Na+:21].[O-:60][C:61]([O-:62])=[O:63].[O:64]=[CH:65][N:66]([CH3:67])[CH3:68]>>[F:1][CH:2]1[CH2:3][CH:4]([C:7](=[O:8])[N:9]([CH3:10])[CH3:11])[N:5]([C:23]2([c:50]3[c:51]([O:56][CH3:57])[cH:52][cH:53][cH:54][cH:55]3)[C:24](=[O:49])[N:25]([S:33](=[O:34])(=[O:35])[c:36]3[c:37]([O:44][C:45]([F:46])([F:47])[F:48])[cH:38][c:39]([O:42][CH3:43])[cH:40][cH:41]3)[c:26]3[cH:27][cH:28][c:29]([Cl:32])[cH:30][c:31]32)[CH2:6]1

Participants

10

Reactant 9

HCID 813Potassium Cation2×HCID 923Sodium ionHCID 6228DimethylformamideHCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 3280088Npc316347HCID 231206824-fluoro-N,N-dimethylpyrrolidine-2-carboxamideHCID 674293293,5-dichloro-3-(2-methoxyphenyl)-1-{[4-methoxy-2-(trifluoromethoxy)phenyl]sulfonyl}-1,3-dihydro-2H-indol-2-one

Product 1

HCID 1784928401-[5-chloro-3-(2-methoxyphenyl)-1-[4-methoxy-2-(trifluoromethoxy)phenyl]sulfonyl-2-oxoindol-3-yl]-4-fluoro-N,N-dimethylpyrrolidine-2-carboxamide

Sources & evidence

ORD record
ord-cff8517b3947451d9ddd9cfd79de3b44
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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