N,N-Diethyl-p-phenylenediamine → 6-Chloro-2-(4-(diethylamino)phenylamino)nicotinamide
Reaction equation
[CH2:12]([CH3:13])[N:14]([c:15]1[cH:16][cH:17][c:18]([NH2:21])[cH:19][cH:20]1)[CH2:22][CH3:23].[CH2:34]1[O:35][CH2:36][CH2:37][CH2:38]1.[CH3:24][Si:25]([N-:26][Si:27]([CH3:28])([CH3:29])[CH3:30])([CH3:31])[CH3:32].[Cl:1][c:2]1[c:3]([C:4](=[O:5])[NH2:6])[cH:7][cH:8][c:9]([Cl:11])[n:10]1.[Li+:33]>>[c:2]1([NH:21][c:18]2[cH:17][cH:16][c:15]([N:14]([CH2:12][CH3:13])[CH2:22][CH3:23])[cH:20][cH:19]2)[c:3]([C:4](=[O:5])[NH2:6])[cH:7][cH:8][c:9]([Cl:11])[n:10]1Participants
6
Sources & evidence
- ORD record
- ord-5bdd74d61c684f72a2c41f347c57cd7f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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