Tetrahydrofuran → 4-[2-Chloro-9-methyl-6-(3-methylmorpholin-4-yl)purin-8-yl]oxan-4-ol
Reaction equation
[CH2:34]1[O:35][CH2:36][CH2:37][CH2:38]1.[CH:19]([N-:20][CH:21]([CH3:22])[CH3:23])([CH3:24])[CH3:25].[Cl:1][c:2]1[n:3][c:4]([N:12]2[CH:13]([CH3:18])[CH2:14][O:15][CH2:16][CH2:17]2)[c:5]2[n:6][cH:7][n:8]([CH3:11])[c:9]2[n:10]1.[Li+:26].[O:27]1[CH2:28][CH2:29][C:30](=[O:33])[CH2:31][CH2:32]1>>[Cl:1][c:2]1[n:3][c:4]([N:12]2[CH:13]([CH3:18])[CH2:14][O:15][CH2:16][CH2:17]2)[c:5]2[n:6][c:7]([C:30]3([OH:33])[CH2:29][CH2:28][O:27][CH2:32][CH2:31]3)[n:8]([CH3:11])[c:9]2[n:10]1Participants
6
Sources & evidence
- ORD record
- ord-55f4d56e659e4828a8e28269c11bebf4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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