4-Methylmorpholine → N-[4-(3-Bromo-phenylamino)-3-cyano-7-methoxy-quinolin-6-yl]-acrylamide
Reaction equation
[C:31]([CH:32]=[CH2:33])(=[O:34])[Cl:35].[CH3:24][N:25]1[CH2:26][CH2:27][O:28][CH2:29][CH2:30]1.[CH3:41][CH2:42][O:43][C:44](=[O:45])[CH3:46].[NH2:1][c:2]1[cH:3][c:4]2[c:5]([NH:16][c:17]3[cH:18][c:19]([Br:23])[cH:20][cH:21][cH:22]3)[c:6]([C:14]#[N:15])[cH:7][n:8][c:9]2[cH:10][c:11]1[O:12][CH3:13].[O:36]1[CH2:37][CH2:38][CH2:39][CH2:40]1>>[NH:1]([c:2]1[cH:3][c:4]2[c:5]([NH:16][c:17]3[cH:18][c:19]([Br:23])[cH:20][cH:21][cH:22]3)[c:6]([C:14]#[N:15])[cH:7][n:8][c:9]2[cH:10][c:11]1[O:12][CH3:13])[C:31]([CH:32]=[CH2:33])=[O:34]Participants
6
Sources & evidence
- ORD record
- ord-a7a75bc0b0c94f07b2b25bea8af0ff68
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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