1,2-Dichloroethane → 10-Hydroxy-10-(4-ethoxybutyl)-2,3,4,10-tetrahydropyrimido[1,2-a]indole

HRID 1541889Notes

Reaction equation

[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][O:6][CH2:7][CH3:8].[Cl-:24].[Cl:26][CH2:27][CH2:28][Cl:29].[Mg:9].[N:10]1=[C:15]2[N:14]([CH2:13][CH2:12][CH2:11]1)[c:22]1[c:17]([cH:18][cH:19][cH:20][cH:21]1)[C:16]2=[O:23].[NH4+:25]>>[CH2:2]([CH2:3][CH2:4][CH2:5][O:6][CH2:7][CH3:8])[C:16]1([OH:23])[C:15]2=[N:10][CH2:11][CH2:12][CH2:13][N:14]2[c:22]2[c:17]1[cH:18][cH:19][cH:20][cH:21]2

Participants

Reactant 6

HCID 111,2-Dichloroethane

HCID 223Ammonium

HCID 312Chloride

HCID 5462224Magnesium

HCID 64275731-Bromo-4-ethoxybutane

HCID 141813833,4-Dihydropyrimido(1,2-a)indol-10(2h)-one

Product 1

HCID 1418139910-Hydroxy-10-(4-ethoxybutyl)-2,3,4,10-tetrahydropyrimido[1,2-a]indole

Sources & evidence

ORD record: ord-257b081240b4494997021dbd27fcecb3
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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