Acetic Acid → 2-(5-Bromo-2-chloropyrimidin-4-yl)-benzo[b]thiophene-4-carboxylic acid
Reaction equation
[Br:18][c:19]1[cH:20][n:21][c:22]([Cl:25])[n:23][cH:24]1.[CH2:41]1[O:42][CH2:43][CH2:44][CH2:45]1.[CH3:46][C:47](=[O:48])[OH:49].[Cl:26][C:27]1=[C:38]([Cl:39])[C:36](=[O:37])[C:33]([C:34]#[N:35])=[C:30]([C:31]#[N:32])[C:28]1=[O:29].[ClH:40].[Li:1][CH2:2][CH2:3][CH2:4][CH3:5].[s:6]1[c:7]2[c:8]([cH:9][cH:10]1)[c:11]([C:15](=[O:16])[OH:17])[cH:12][cH:13][cH:14]2>>[s:6]1[c:7]2[c:8]([cH:9][c:10]1-[c:20]1[c:19]([Br:18])[cH:24][n:23][c:22]([Cl:25])[n:21]1)[c:11]([C:15](=[O:16])[OH:17])[cH:12][cH:13][cH:14]2Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-e6814d771e6240cca3d146173f268196
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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