Ammonium → 5-chloro-N-(2,4-dimethoxybenzyl)-2,4-difluoro-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide

HRID 1542345Notes

Reaction equation

HRID 1542345 reaction equation
[C:43]([O:44][CH:45]([CH3:46])[CH3:47])(=[O:48])[CH3:49].[CH3:18][Si:19]([N-:20][Si:21]([CH3:22])([CH3:23])[CH3:24])([CH3:25])[CH3:26].[CH3:1][O:2][c:3]1[c:4]([CH2:5][NH:6][c:7]2[s:8][cH:9][n:10][n:11]2)[cH:12][cH:13][c:14]([O:16][CH3:17])[cH:15]1.[CH3:50][CH:51]1[CH2:52][CH2:53][CH2:54][O:55]1.[Cl-:41].[Cl:28][c:29]1[c:30]([F:40])[cH:31][c:32]([F:39])[c:33]([S:35](=[O:36])(=[O:37])[Cl:38])[cH:34]1.[Li+:27].[NH4+:42].[OH2:56]>>[CH3:1][O:2][c:3]1[c:4]([CH2:5][N:6]([c:7]2[s:8][cH:9][n:10][n:11]2)[S:35]([c:33]2[c:32]([F:39])[cH:31][c:30]([F:40])[c:29]([Cl:28])[cH:34]2)(=[O:36])=[O:37])[cH:12][cH:13][c:14]([O:16][CH3:17])[cH:15]1

Participants

10

Reactant 9

HCID 223AmmoniumHCID 312ChlorideHCID 962WaterHCID 73012-MethyltetrahydrofuranHCID 7915Isopropyl AcetateHCID 28486Lithium ionHCID 27735275-Chloro-2,4-difluorobenzenesulphonyl chlorideHCID 3280088Npc316347HCID 58042278N-(2,4-dimethoxybenzyl)-1,3,4-thiadiazol-2-amine

Product 1

HCID 580422535-chloro-N-(2,4-dimethoxybenzyl)-2,4-difluoro-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide

Sources & evidence

ORD record
ord-e8294398097a4100ab22db25c46f300e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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