proline dl-form → HCID 57496303, compound

HRID 154327Notes

Reaction equation

HRID 154327 reaction equation
[C:43](=[O:44])([O-:45])[O-:46].[CH2:31]([CH2:32][CH3:33])[NH2:34].[CH3:49][S:50]([CH3:51])=[O:52].[CH:1]([CH3:2])([CH3:3])[O:4][C:5](=[O:6])[N:7]1[CH2:8][CH2:9][CH:10]([O:13][c:14]2[c:15]3[c:16]([n:17][cH:18][n:19]2)[n:20](-[c:23]2[c:24]([CH3:30])[cH:25][c:26]([I:29])[cH:27][cH:28]2)[n:21][cH:22]3)[CH2:11][CH2:12]1.[Cu:53]([I:54])[I:55].[K+:47].[K+:48].[OH:35][C:36]([CH:37]1[NH:38][CH2:39][CH2:40][CH2:41]1)=[O:42]>>[CH:1]([CH3:2])([CH3:3])[O:4][C:5](=[O:6])[N:7]1[CH2:8][CH2:9][CH:10]([O:13][c:14]2[c:15]3[c:16]([n:17][cH:18][n:19]2)[n:20](-[c:23]2[c:24]([CH3:30])[cH:25][c:26]([NH:34][CH2:31][CH2:32][CH3:33])[cH:27][cH:28]2)[n:21][cH:22]3)[CH2:11][CH2:12]1

Participants

8

Reactant 7

HCID 614proline dl-formHCID 679Dimethyl SulfoxideHCID 813Potassium Cation2×HCID 7852PropylamineHCID 19660Carbonate IonHCID 83717Copper iodideHCID 574963694-[1-(4-iodo-2-methyl-phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy]-piperidine-1-carboxylic acid isopropyl ester

Product 1

HCID 57496303HCID 57496303, compound

Sources & evidence

ORD record
ord-13bbd54dc2ea4e8e98b87d4a9dcd60a8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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